My Top Gut Supplements for Immunity

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Note: I am not a physician and I do not diagnose or treat disease. Before starting any new health protocol, please consult with your supervising physician, especially if pregnant, elderly, or taking medications.

These practitioner-grade supplements are effective! But many people in our community have had a chronic health imbalance for many years. Making a change to your microbiome, even a positive one, can have temporary side effects. This is not necessarily a bad thing, but you do need to know how to manage it, which is usually lowering the dose. Please download and read our Guide to Managing Side Effects for a very clear explanation of all this!

I’m going to keep this one short! Here’s my list of top supplements for gut immunity:

1. MegaSporeBiotic 

  • Contains bacillus strains can reduce the frequency and duration of respiratory infections

  • Reduces LPS endotoxins which stimulate ACE receptors that are targets for COVID

  • Contains spores, which can survive stomach acid to populate and direct the microbiome

  • Is anti-inflammatory, antioxidant and promotes healthy mucosa growth

Dosage: 1/2 capsule daily low dose, 2 capsules a day typical dose, 4 a day high dose. Take with a protein meal.


2. MegaPrebiotic Fiber

  • Feeds only friendly bacteria and keystone strains of probiotics

  • Provides keystone strains prevent chronic disease (1).

  • Contains kiwi fruit which protects against upper respiratory infections (2)

Dosage: Start with 1/4 dose in water and work up to 1 dose in water sipped throughout the day.

3. Mega IgG 2000

  • Contains IgG antibodies, which attach to antigens (foreign substances and biological toxins)

  • Is effective against bacteria and viruses

  • Prevents leaky gut

Dosage: Ideally, take 4 per day, but this can cause cramping or constipation due changing in bowel patterns so start with 1 a day with a meal and increase slowly, as tolerated.

4. Omega Concentrate

  • “Inflammation drives dysbiosis” -Kiran Krishnan

  • COVID inflames gut lining

  • Dysbiosis “promotes and worsens upper airway infections” (3) 

  • Omega Concentrate contains EPA, DPA, and PRM fatty acids compounds, which reduce inflammation

  • Omega Concentrate also contains DHA for brain performance

Dosage: Typical dosing is just 2 a day. Consider doubling up for significant bowel inflammation or acute infection.

5. MegaMycobalance

  • Contains propolis, an immune modulator that decreases Candida overgrowth

  • Prohibits Candida overgrowth, which compromises immune function (4)

  • Contains undecylenic acid that prevents Candida from creating biofilms (5)

  • Fights Candida, and symptoms may include brain fog, sugar cravings, fatigue, and swollen glands

Dosage: Work up to 2 capsules twice a day as tolerated.

6. MegaGuard (Bonus!)

This is a similarly simple formula but its effects are broad. It helps with:

  • Licorice flavonoids support HCL production to prevent bloating/ SIBO.

  • Artichoke extract increases bile production for detox, SIBO and fat digestion

  • Ginger supports the movement of the intestines and prevents putrification 

  • Also addresses H Pylori infections

Dosage: Work up to 2 capsules with lunch and dinner and tolerated.

Shop Microbiome Labs products at HormoneDetoxShop.com!

We offer free shipping for all US orders over $97, and new customers can snag 10% off their first order with the code “WELCOME10.”

For the “feature-length” video on COVID-19, immunity, inflammation and the gut, please enjoy my interview with microbiologist and Microbiome Labs co-founder, Kiran Krishnan:

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Science-Backed Supplements for Safe Immune Support

Are you wondering how to best support your immunity? Theories abound, but not all of them are based on facts. In this book,  I only present the information I can back up. I’ll do some myth-busting and share some information on dealing with pre-existing conditions and keeping your immunity strong!

Grab my guide to arm yourself with the healthy facts!


Bridgit Danner, LAc, FDNP, is trained in functional health coaching and has worked with thousands of women over her career since 2004. She is the founder of Women’s Wellness Collaborative llc and HormoneDetoxShop.com.